Ruma Banerjee’s research focuses on the structural enzymology of human B12 trafficking proteins and the chemical biology of hydrogen sulfide signaling and homeostasis with a focus on the three-way interaction between diet, microbial and host energy metabolism. Her contributions have been recognized by her election to the American Academy of Arts and Sciences, the Merck (from the ASBMB) and the Pfizer (from the ACS) awards. She is also a fellow of the ASBMB and the American Association for the Advancement of Sciences. She was the founding Director of the NIH-funded Redox Biology Center and has trained >100 students and postdoctoral fellows. She is deeply committed to mentoring and is the founding co-Director of ASBMB’s NIH-funded MOSAIC program. She currently serves on the editorial board on Biochemistry and Trends in Chemistry and was an associate editor for >10 years for Chemical Reviews and the Journal of Biological Chemistry.